A rash of bizarre murders in New York City seems to point to a group of grotesquely deformed vagrants living in the sewers. A courageous policeman, a photo journalist and his girlfriend, and a nutty bum, who seems to know a lot about the creatures, band together to try and determine what the creatures are and how to stop them.
Adventurer/surgeon/rock musician Buckaroo Banzai and his band of men, the Hong Kong Cavaliers, take on evil alien invaders from the 8th dimension.
A government funded project looks into using psychics to enter people’s dreams, with some mechanical help. When a subject dies in his sleep from a heart attack Alex Gardner becomes suspicious that another of the psychics is killing people in the dreams somehow and that is causing them to die in real life. He must find a way to stop the abuse of the power to enter dreams.