A woman with psychic powers has a vision of a murder that took place in a house owned by her husband.
In 1959 Dover, England, a woman commits suicide by leaping from a cliff. At the same time, her daughter Virginia, living in Florence, Italy sees her mother’s death in a vision. In the present day, an adult Virginia (Jennifer O’Neill) lives near Rome, Italy and has married a rich Italian businessman Francesco Ducci (Gianni Garko). Ducci leaves on a business trip, and as Virginia drives herself away from the airport after seeing him off, experiences more visions—she sees an old woman murdered, a wall being torn down and a letter hidden beneath a statue.
Virginia plans to renovate an abandoned mansion her husband has bought, but notices that the building resembles one she has seen in her visions. She tears down a wall in one room, finding a skeleton behind the plaster. Assuming the skeleton is that of the woman in her vision, Virginia contacts the police; however, they do not believe her story and charge Ducci with the killing.
Examination of the body reveals it not to be an old woman, but one in her twenties; killed about five years earlier. The skeleton is finally identified as Ducci’s ex-girlfriend, who vanished several years ago. Virginia is determined to exculpate her husband, and contacts her friend Luca Fattori (Marc Porel). Fattori is a researcher of psychic phenomena, and his investigation eventually leads to the wealthy Emilio Rospini (Gabriele Ferzetti), who may be the true culprit.
Francesco returns from his business trip where Virginia updates him on everything that has happened. He urges her to dismiss the matter from her mind, but she instead grows more and more obsessed with learning this mystery.
Virginia discusses the case with Francesco’s sister Gloria (Evelyn Stewart), and Melli (Riccardo Parisio Perrotti), a lawyer friend of Gloria’s. Gloria says that her brother left for a business trip to America in April 1972, and that she was the one who changed the furniture of the place. The room with the walled-in corpse had been Franceso’s bedroom, but was the Gloria who had bought the furniture that Virginia saw in her vision, after Francesco’s departure…