DECADES of evidence reveal that vitamin C attacks cancer through four powerful mechanisms: pro-oxidative cytotoxicity, epigenetic reprogramming, signaling-pathway suppression, and immune activation.
A MASSIVE new paper in Genes & Diseases analyzed 150+ studies and found that when vitamin C reaches true pharmacologic levels (20–30 mM), it behaves like a targeted, tumor-selective therapy — something past trials missed by under-dosing.
The evidence base spans decades of laboratory, animal, and early-phase clinical research.
Key findings ⬇️
✅ At high doses, vitamin C becomes a cancer-killer — generating hydrogen peroxide bursts that destroy cancer cells while sparing healthy cells.
✅ Cancer cells are uniquely vulnerable due to excess iron, heavy vitamin C uptake, and weak antioxidant defenses.
✅ KRAS & BRAF mutant cancers are extremely sensitive — leading to metabolic collapse, dramatic shrinkage, and improved outcomes when high-dose IV vitamin C is added.
✅ Vitamin C shuts down the tumor “survival switch” (HIF-1α) — blocking blood-vessel growth, metastasis programs, and hypoxia-driven tumor survival.
✅ It reprograms cancer DNA — reversing abnormal methylation and reactivating tumor-suppressor genes through TET enzyme activation.
✅ It boosts anti-tumor immunity — more CD4+/CD8+ T cells, stronger NK and γδ T-cell activity, higher IL-12 & granzyme B, and enhanced response to PD-1/CTLA-4 immunotherapy.
✅ Human trials already show real benefits — pancreatic tumor shrinkage, longer survival in glioblastoma, higher response rates in lung cancer, and lower chemo toxicity.
✅ Effective dosing is high: 75–100 g IV (or >1 g/kg), 2–3× per week — the level required to hit the true cancer-killing range.
Bottom line: High-dose IV vitamin C is a multi-mechanism, tumor-targeting anti-cancer therapy that has been underestimated for decades — and now deserves modern Phase III trials.
Cheap Antiparasitic Fenbendazole Linked to COMPLETE REMISSION of Stage IV Cancers
Advanced melanoma, breast & prostate cancer patients saw tumors VANISH — without chemotherapy.
Clinical trials must be launched immediately as cancer rates skyrocket.
[Via: @NicHulscher @MakisMedicine]