Via @MakisMedicine:
This time, it’s the Pfiz3r and M0derna Lipid Nanoparticles (LNPs).
“LNP administration promotes tumor metastasis by inducing a systemic inflammatory response”
“LNP injection triggered acute neutrophil accumulation in the lungs, driven by the release of mitochondrial DNA (mtDNA) from necrotic muscle cells at the injection site.”
“This mtDNA-mediated signaling activated the TLR9-MyD88 and cGAS-STING pathways, leading to neutrophil extracellular trap (NET) formation, which facilitated the establishment of a pro-metastatic niche”
[Also via: Dr. Seneff @stephanieseneff]